Tdap Vaccination During Pregnancy
The short answer
The Tdap vaccine (tetanus, diphtheria, and pertussis/whooping cough) is recommended during every pregnancy, ideally between weeks 27-36 of the third trimester. This allows the birthing parent to produce antibodies that cross the placenta, protecting the newborn from pertussis during their first vulnerable months before they can receive their own vaccines.
Parents everywhere have the same worry. You are doing the right thing by looking into it.
By Age
What to expect by age
ACOG and CDC recommend Tdap between 27-36 weeks of each pregnancy, regardless of when you last received the vaccine. Earlier administration in this window gives more time for antibody production and transfer. The vaccine is safe and does not increase risk of preterm labor or adverse outcomes. Mild side effects include sore arm and low-grade fever.
What Should You Do?
When to take action
- Mild soreness at the injection site
- Low-grade fever or fatigue for 1-2 days after vaccination
- Getting Tdap in each pregnancy even if previously vaccinated
- You have questions about vaccine timing or safety
- You had a previous adverse reaction to a vaccine
- You missed the recommended window and want to discuss options
- Severe allergic reaction after vaccination (very rare): difficulty breathing, swelling of face/throat, hives - seek emergency care
Sources
Related Resources
Trust your instincts. If something feels wrong, reach out to your pediatrician.
Worrying about your baby means you care. That is a good thing.
Related Maternal Concerns
Influenza Vaccine in Pregnancy
The flu shot is recommended for all pregnant people during any trimester of pregnancy. Pregnant people are at higher risk for severe flu complications due to immune system and cardiopulmonary changes. The inactivated flu vaccine is safe and protects both you and your baby (through transferred antibodies) during the first months of life. The nasal spray flu vaccine should NOT be used during pregnancy.
COVID Vaccination During Pregnancy
COVID-19 vaccination is recommended during pregnancy by ACOG, CDC, and other major health organizations. COVID-19 infection during pregnancy significantly increases the risk of severe illness, ICU admission, preterm birth, and stillbirth. The mRNA vaccines (Pfizer, Moderna) have been extensively studied in pregnant people and shown to be safe and effective.
Dealing with Abnormal Prenatal Screening Results
An abnormal prenatal screening result can be terrifying, but it is important to understand that screening tests are designed to cast a wide net and have significant false-positive rates. Most people with abnormal screening results go on to have healthy babies after further testing confirms the baby is fine. An abnormal screening is a reason for more information, not a diagnosis.
Pregnancy Over 35 (Advanced Maternal Age)
While pregnancy after 35 carries some increased risks (including chromosomal abnormalities, gestational diabetes, and hypertension), the vast majority of people over 35 have healthy pregnancies and healthy babies. The term "geriatric pregnancy" is outdated and does not reflect reality. With appropriate prenatal care and monitoring, outcomes are excellent.
Amniocentesis Questions and Fears
Amniocentesis is a diagnostic test performed between 15-20 weeks that analyzes amniotic fluid to detect chromosomal conditions and genetic disorders with over 99% accuracy. The risk of pregnancy loss from the procedure is approximately 1 in 500-1,000 when performed by an experienced provider. Understanding the actual risks can help you make an informed decision.
20-Week Anatomy Scan Unexpected Findings
The 20-week anatomy scan checks your baby's major organs, structures, and growth. Most scans are completely normal. When unexpected findings are identified, they range from minor variants that resolve on their own to conditions that need further evaluation. Many findings require nothing more than a follow-up ultrasound to confirm the baby is developing well.